Archives of Oral Biology
Volume 54, Issue 8 , Pages 705-716 , August 2009

Characterisation of the constitutive over-expression of AJ18 in a novel rat stromal bone marrow cell line (D8-SBMC)

  • Andrew Jheon

      Affiliations

    • Department of Orthopaedic Surgery, University of California at San Francisco, 533 Parnassus Ave. U470, San Francisco, CA 94143, United States
  • ,
  • Anil K. Bansal

      Affiliations

    • Nova Century Scientific Inc., 5022 South Service Road, Burlington, ON, Canada L7L 5Y7
  • ,
  • Baoqian Zhu

      Affiliations

    • CIHR Group in Matrix Dynamics, University of Toronto, 150 College St. #234, Toronto, ON, Canada M5S 3E2
  • ,
  • Bernhard Ganss

      Affiliations

    • CIHR Group in Matrix Dynamics, University of Toronto, 150 College St. #234, Toronto, ON, Canada M5S 3E2
    • Corresponding Author InformationCorresponding author. Tel.: +1 416 978 8728; fax: +1 416 978 5956.
  • ,
  • Sela Cheifetz

      Affiliations

    • CIHR Group in Matrix Dynamics, University of Toronto, 150 College St. #234, Toronto, ON, Canada M5S 3E2
  • ,
  • Jaro Sodek

      Affiliations

    • CIHR Group in Matrix Dynamics, University of Toronto, 150 College St. #234, Toronto, ON, Canada M5S 3E2

,Accepted 21 April 2009.

References 

  1. Kotev-Emeth S, Pitaru S, Pri-Chen S, Savion N. Establishment of a rat long-term culture expressing the osteogenic phenotype: dependence on dexamethasone and FGF-2. Connect Tissue Res. 2002;43(4):606–612
  2. Pitaru S, Kotev-Emeth S, Noff D, Kaffuler S, Savion N. Effect of basic fibroblast growth factor on the growth and differentiation of adult stromal bone marrow cells: enhanced development of mineralized bone-like tissue in culture. J Bone Miner Res. 1993;8(8):919–929
  3. Krebsbach PH, Kuznetsov SA, Bianco P, Robey PG. Bone marrow stromal cells: characterization and clinical application. Crit Rev Oral Biol Med. 1999;10(2):165–181
  4. Owen M. Marrow stromal stem cells. J Cell Sci Suppl. 1988;10:63–76
  5. Owen M, Friedenstein AJ. Stromal stem cells: marrow-derived osteogenic precursors. Ciba Found Symp. 1988;136:42–60
  6. Ashton BA, Abdullah F, Cave J, Williamson M, Sykes BC, Couch M, et al. Characterization of cells with high alkaline phosphatase activity derived from human bone and marrow: preliminary assessment of their osteogenicity. Bone. 1985;6(5):313–319
  7. Latsinik NV, Gorskaia Iu F, Grosheva AG, Domogatskii SP, Kuznetsov SA. The stromal colony-forming cell (CFUf) count in the bone marrow of mice and the clonal nature of the fibroblast colonies they form. Ontogenez. 1986;17(1):27–36
  8. Friedenstein AJ, Ivanov-Smolenski AA, Chajlakjan RK, Gorskaya UF, Kuralesova AI, Latzinik NW, et al. Origin of bone marrow stromal mechanocytes in radiochimeras and heterotopic transplants. Exp Hematol. 1978;6(5):440–444
  9. Bellows CG, Aubin JE, Heersche JN, Antosz ME. Mineralized bone nodules formed in vitro from enzymatically released rat calvaria cell populations. Calcif Tissue Int. 1986;38:143–154
  10. Yao KL, Todescan R, Sodek J. Temporal changes in matrix protein synthesis and mRNA expression during mineralized tissue formation by adult rat bone marrow cells in culture. J Bone Miner Res. 1994;9(2):231–240
  11. Partridge NC, Alcorn D, Michelangeli VP, Ryan G, Martin TJ. Morphological and biochemical characterization of four clonal osteogenic sarcoma cell lines of rat origin. Cancer Res. 1983;43:4308–4314
  12. Majeska RJ, Rodan SB, Rodan GA. Parathyroid hormone-responsive clonal cell lines from rat osteosarcoma. Endocrinology. 1980;107:1494–1503
  13. Reznikoff CA, Brankow DW, Heidelberger C. Establishment and characterization of a cloned line of C3H mouse embryo cells sensitive to postconfluence inhibition of division. Cancer Res. 1973;33(12):3231–3238
  14. Sudo H, Kodama HA, Amagai Y, Yamamoto S, Kasai S. In vitro differentiation and calcification in a new clonal osteogenic cell line derived from newborn mouse calvaria. J Cell Biol. 1983;96:191–198
  15. Barragan-Adjemian C, Nicolella D, Dusevich V, Dallas MR, Eick JD, Bonewald LF. Mechanism by which MLO-A5 late osteoblasts/early osteocytes mineralize in culture: similarities with mineralization of lamellar bone. Calcif Tissue Int. 2006;79(5):340–353
  16. Kato Y, Boskey A, Spevak L, Dallas M, Hori M, Bonewald LF. Establishment of an osteoid preosteocyte-like cell MLO-A5 that spontaneously mineralizes in culture. J Bone Miner Res. 2001;16(9):1622–1633
  17. Karsenty G. The complexities of skeletal biology. Nature. 2003;423:316–318
  18. Karsenty G, Wagner EF. Reaching a genetic and molecular understanding of skeletal development. Dev Cell. 2002;2(4):389–406
  19. Ducy P, Schinke T, Karsenty G. The osteoblast: a sophisticated fibroblast under central surveillance. Science. 2000;289(5484):1501–1504
  20. Komori T, Yagi H, Nomura S, Yamaguchi A, Sasaki K, Deguchi K, et al. Targeted disruption of Cbfa1 results in a complete lack of bone formation owing to maturational arrest of osteoblasts. Cell. 1997;89(5):755–764
  21. Ducy P, Zhang R, Geoffrey V, Ridall AL, Karsenty G. Osf 2 Cbfa1: a transcriptional activator of osteoblast differentiation. Cell. 1997;89:747–754
  22. Nakashima K, Zhou X, Kunkel G, Zhang Z, Deng JM, Behringer RR, et al. The novel zinc finger-containing transcription factor osterix is required for osteoblast differentiation and bone formation. Cell. 2002;108(1):17–29
  23. Nishio Y, Dong Y, Paris M, O’Keefe RJ, Schwarz EM, Drissi H. Runx2-mediated regulation of the zinc finger Osterix/Sp7 gene. Gene. 2006;372:62–70
  24. Jheon AH, Ganss B, Cheifetz S, Sodek J. Characterization of a novel KRAB/C2H2 zinc finger transcription factor involved in bone development. Journal of Biological Chemistry. 2001;276(21):18282–18289
  25. Ganss B, Jheon A. Zinc finger transcription factors in skeletal development. Crit Rev Oral Biol Med. 2004;15(5):282–297
  26. Jheon A, Ganss B, Cheifetz S, Sodek J. Identification of a novel zinc finger transcription factor target of bone morphogenetic protein-7 in osteogenesis. J Am Acad Ortho Surg. 1998;15:87–91
  27. Jheon A, Chen J, Teo W, Ganss B, Sodek J, Cheifetz S. Temporal and spatial expression of a novel zinc finger transcription factor, AJ18, in developing murine skeletal tissues. J Histochem Cytochem. 2002;50(7):973–982
  28. Helder MN, Ozkaynak E, Sampath KT, Latin V, Oppermann H, Vukicevic S. Expression pattern of osteogenic protein-1 (bone morphogenetic protein-7) in human and mouse development. J Histochem Cytochem. 1995;43:1035–1044
  29. Sampath TK, Maliakal JC, Hauschka PV, Jones WK, Sasak H, Tucker RF, et al. Recombinant human osteogenic protein-1 (hOP-1) induces new bone formation in vivo with a specific activity comparable with natural bovine osteogenic protein and stimulates osteoblast proliferation and differentiation in vitro. J Biol Chem. 1992;267(28):20352–20362
  30. Jheon AH, Suzuki N, Nishiyama T, Cheifetz S, Sodek J, Ganss B. Characterization of the 5’-flanking region of the rat AJ18 gene. Gene. 2003;310:203–213
  31. Maniatopoulos C, Sodek J, Melcher AH. Bone formation in vitro by stromal cells obtained from bone marrow of young adult rats. Cell Tissue Res. 1988;254(2):317–330
  32. McKee MD, Nanci A. Postembedding colloidal-gold immunocytochemistry of noncollagenous extracellular matrix proteins in mineralized tissues. Microsc Res Technol. 1995;31(1):44–62
  33. Hincke MT, Chien YC, Gerstenfeld LC, McKee MD. Colloidal-gold immunocytochemical localization of osteopontin in avian eggshell gland and eggshell. J Histochem Cytochem. 2008;56(5):467–476
  34. Nagata T, Todescan R, Goldberg HA, Zhang Q, Sodek J. Sulphation of secreted phosphoprotein I (SPPI, osteopontin) is associated with mineralized tissue formation. Biochem Biophys Res Commun. 1989;165(1):234–240
  35. Domenicucci C, Goldberg HA, Hofmann T, Isenman D, Wasi S, Sodek J. Characterization of porcine osteonectin extracted from foetal calvariae. Biochem J. 1988;253(1):139–151
  36. Fisher LW, Stubbs JT, Young MF. Antisera and cDNA probes to human and certain animal model bone matrix noncollagenous proteins. Acta Orthop Scand Suppl. 1995;266:61–65
  37. Mulari MT, Qu Q, Harkonen PL, Vaananen HK. Osteoblast-like cells complete osteoclastic bone resorption and form new mineralized bone matrix in vitro. Calcif Tissue Int. 2004;75(3):253–261
  38. Kasugai S, Todescan R, Nagata T, Yao KL, Butler WT, Sodek J. Expression of bone matrix proteins associated with mineralized tissue formation by adult rat bone marrow cell in vitro: inductive effects of dexamethasone on the osteoblastic phenotype. J Cell Physiol. 1991;147(1):111–120
  39. Posner AS. The mineral of bone. Clin Orthop Relat Res. 1985;200:87–99
  40. Davies JE, Hosseini MM. Histodynamics of endosseous wound healing. In:  Davies JE editors. Bone Engineering. Toronto: Em Squared, Inc. Elsevier; 2000;p. 1–14
  41. Davies JE. Bone bonding at natural and biomaterial surfaces. Biomaterials. 2007;28(34):5058–5067
  42. Wennberg C, Hessle L, Lundberg P, Mauro S, Narisawa S, Lerner UH, et al. Functional characterization of osteoblasts and osteoclasts from alkaline phosphatase knockout mice. J Bone Miner Res. 2000;15(10):1879–1888
  43. Drissi H, Luc Q, Shakoori R, Chuva De Sousa Lopes S, Choi JY, Terry A, et al. Transcriptional autoregulation of the bone related CBFA1/RUNX2 gene. J Cell Physiol. 2000;184(3):341–350
  44. Komori T. Regulation of bone development and maintenance by Runx2. Front Biosci. 2008;13:898–903
  45. Young DW, Hassan MQ, Pratap J, Galindo M, Zaidi SK, Lee SH, et al. Mitotic occupancy and lineage-specific transcriptional control of rRNA genes by Runx2. Nature. 2007;445(7126):442–446
  46. Ali SA, Zaidi SK, Dacwag CS, Salma N, Young DW, Shakoori AR, et al. Phenotypic transcription factors epigenetically mediate cell growth control. Proc Natl Acad Sci USA. 2008;105(18):6632–6637
  47. Huang Z, Philippin B, O’Leary E, Bonventre JV, Kriz W, Witzgall R. Expression of the transcriptional repressor protein Kid-1 leads to the disintegration of the nucleolus. J Biol Chem. 1999;274(12):7640–7648
  48. Lee MH, Kim YJ, Kim HJ, Park HD, Kang AR, Kyung HM, et al. BMP-2-induced Runx2 expression is mediated by Dlx5, and TGF-beta 1 opposes the BMP-2-induced osteoblast differentiation by suppression of Dlx5 expression. J Biol Chem. 2003;278(36):34387–34394

PII: S0003-9969(09)00096-X

doi: 10.1016/j.archoralbio.2009.04.007

Archives of Oral Biology
Volume 54, Issue 8 , Pages 705-716 , August 2009