Archives of Oral Biology
Volume 55, Issue 3 , Pages 215-222 , March 2010

IGF-I, IGF-IR and IRS1 expression as an early reaction of PDL cells to experimental tooth movement in the rat

,Accepted 6 January 2010.

References 

  1. Krishnan V, Davidovitch Z. Cellular, molecular, and tissue-level reactions to orthodontic force. Am J Orthod Dentofacial Orthop. 2006;129:469e.1–32
  2. Masella RS, Meister M. Current concepts in the biology of orthodontic tooth movement. Am J Orthod Dentofacial Orthop. 2006;129:458–468
  3. Clemmons DR, Maile LA. Interaction between Insulin-like growth factor-I receptor and Vβ3 integrin linked signaling pathways: cellular responses to changes in multiple signaling inputs. Mol Endocrinol. 2005;19:1–11
  4. Rosen CJ. Serum insulin-like growth factors and insulin-like growth factors-binding proteins: clinical implications. Clin Chem. 1999;45:1384–1390
  5. Denley A, Cosgrove LJ, Booker GW, Wallace JC, Forbes BE. Molecular interactions of the IGF system. Cytokine Growth Factor Rev. 2005;16:421–439
  6. Laron Z. Insulin like growth factor 1 (IGF-1): a growth hormone. J Clin Pathol. 2001;54:311–316
  7. Zofkova I. Pathophysiological and clinical importance of insulin-like growth factor-1 with respect to bone metabolism. Physiol Res. 2003;52:657–679
  8. Jones JI, Clemmons DR. Insulin-like growth factors and their binding proteins: biological actions. Endocr Rev. 1995;16:3–34
  9. Mauro L, Surmacz E. IGF-I receptor, cell-cell adhesion, tumor development and progression. J Mol Histol. 2004;35:247–253
  10. Romano G. The complex biology of the receptor for the insulin-like growth factor-1. Drug News Perspect. 2003;16:225–231
  11. Ogata N, Chikazu D, Kubota N, Terauchi Y, Tobe K, Azuma Y, et al. Insulin receptor substrate-1 in osteoblast is indispensable for maintaining bone turnover. J Clin Invest. 2000;105:935–943
  12. Govoni E, Baylink DJ, Mohan S. The multifunctional role of insulin-like growth factor binding proteins in bone. Pediatr Nephrol. 2005;20:261–268
  13. Pavlin D, Gluhak-Heinrich J. Effect of mechanical loading on periodontal cells. Crit Rev Oral Biol Med. 2001;12:414–424
  14. Kostenuik PJ, Halloran BP, Morey-Halton ER, Bikle DD. Skeletal unloading inhibits the in vitro proliferation and differentiation of rat osteoprogenitor cells. Am J Physiol. 1997;273:E1133–E1139
  15. McCarthy TL, Centrella M. Local IGF-I expression and bone formation. Growth Horm IGF Res. 2001;11:213–219
  16. Bouletreau PJ, Warren SM, Longaker MT. The molecular biology of distraction osteogenesis. J Craniomaxillofac Surg. 2002;30:1–11
  17. Reijnders CM, Bravenboer N, Tromp AM, Blankenstein MA, Lips P. Effect of mechanical loading on insulin-like growth factor-I gene expression in rat tibia. J Endocrinol. 2007;192:131–140
  18. Götz W, Krüger U, Ragotzki S, Lossdörfer S, Jäger A. Immunohistochemical localization of components of insulin-like growth factor-system in human deciduous teeth. Connect Tissue Res. 2001;42:291–302
  19. Götz W, Heinen M, Lossdörfer S, Jäger A. Immunohistochemical localization of components of insulin-like growth factor-system in human permanent teeth. Arch Oral Biol. 2006;51:387–395
  20. Werner H, Katz J. The emerging role of the Insulin-like growth factors in oral biology. J Dent Res. 2004;83:832–836
  21. Götz W, Kunert D, Zhang D, Kawarizadeh A, Lossdörfer S, Jäger A. Insulin-like growth factor-system components in the periodontium during tooth root resorption and early repair processes in the rat. Eur J Oral Sci. 2006;114:318–327
  22. Kawarizadeh A, Bourauel C, Götz W, Jäger A. Early responses of periodontal ligament cells to mechanical stimulus in vivo. J Dent Res. 2005;84:902–906
  23. Mohan S, Baylink D. Bone growth factors. Clin Orthop Relat Res. 1991;263:30–48
  24. Zhao G, Monier-Faugere MC, Langub MC, Geng Z, Nakayama T, Pike JW, et al. Targeted overexpression of insulin-like growth factor I to osteoblasts of transgenic mice: increased trabicular bone volume without increased osteoblasts proliferation. Endocrinology. 2000;141:2674–2682
  25. Le Roith D, Bondy C, Yakar S, Liu JL, Butler A . The somatomedin hypothesis. Endocr Rev. 2001;22:53–74
  26. Woods KA, Camacho-Hubner C, Savage MO, Clark AJ. Intrauterine growth retardation and postnatal growth failure associated with deletion of the insulin-like growth factor I gene. N Engl J Med. 1996;335:1363–1367
  27. Bonapace G, Concolino D, Formicola S, Strisciuglio P. A novel mutation in a patient with Insulin-like growth factor 1 (IGF1) deficiency. J Med Genet. 2003;40:913–917
  28. Goldspink G. Changes in muscle mass and phenotype and the expression of autocrine and systemic growth factors by muscle in response to stretch and overload. J Anat. 1999;194:323–334
  29. Adams GR, Autocrine/paracrine . IGF-I and skeletal muscle adaptation. J Appl Physiol. 2002;93:1159–1167
  30. Hirukaw K, Miyazawa K, Maeda H, Kameyama Y, Goto S, Togari A. Effect of tensile force on the expression of IGF-I and IGF-I receptor in the organ-cultured rat cranial suture. Arch Oral Biol. 2005;50:367–372
  31. Hajjar D, Santos MF, Kimura IT. Propulsive appliance stimulates the synthesis of insulin-like growth factors I and II in the mandibular condylar cartilage of young rats. Arch Oral Biol. 2003;48:635–642
  32. Farhadieh RD, Dickinson R, Yu Y, Gianutsos MP, Walsh WR. The role of transforming growth factor, insulin like growth factor I, and basic fibroblast growth factor in distraction osteogenesis of the mandible. J Craniofac Surg. 1999;10:80–86
  33. Yates KE, Troulis MJ, Kaban LB, Glowacki J. IGF-I, TGF-II, and BMP-4 are expressed during distraction osteogenesis of the pig mandible. Int J Oral Maxillofac Surg. 2002;31:173–178
  34. Saggese R, Federico G, Gandini P. The IGF-1–IGFBPs system in the cervicular fluid: its changes during orthodontic movement. Prog Orthod. 2005;6:114–118
  35. Bikle DD, Hallaoran BP. The response of bone to unloading. J Bone Miner Metab. 1999;17:233–244
  36. Kostenuik PJ, Halloran BP, Morey-Halton ER, Bikle DD. Skeletal unloading inhibits the in vitro proliferation and differentiation of rat osteoprogenitor cells. Am J Physiol. 1997;273:1133–1139
  37. Sakata T, Wang Y, Halloran BP, Elalieh HZ, Cao J, Bikle DD. Skeletal unloading induces resistance to Insulin-like growth factor-I (IGF-I) by inhibiting activation of the IGF-I signalling pathways. J Bone Miner Res. 2004;19:436–446
  38. Butler AA, LeRoith D. Tissue-specific versus generalized gene targeting of the igf1 and igf1r genes and their roles in insulin-like growth factor physiology. Endocrinology. 2001;142:1685–1688
  39. Ohlsson C, Sjögren K, Jansson JO, Isaksson OG. The relative importance of endocrine versus autocrine/paracrine insulin-like growth factor-I in the regulation of body growth. Pediatr Nephrol. 2000;14:541–543
  40. Kumasheva RT, Houghton PT. IGF-I mediated survival pathways in normal and malignant cells. Biochim Biophys Acta. 2006;1766:1–22
  41. Han X, Amar S. IGF-1 signaling enhances cell survival in periodontal ligament fibroblasts vs. gingival fibroblasts. J Dent Res. 2003;82:454–459
  42. Palioto DB, Coletta RD, Graner E, Joly JC, de Lima AF. The influence of enamel matrix derivative associated with insulin-like growth factor-I on periodontal ligament fibroblasts. J Periodontol. 2004;75:498–504
  43. Grzesik WJ, Narayanan AS. Cementum and periodontal wound healing and regeneration. Crit Rev Oral Biol. 2002;13:474–484
  44. Wergedal JE, Mohan S, Lundy M, Baylink DJ. Skeletal growth factor and other growth factors known to be present in bone matrix stimulate proliferation and protein synthesis in human bone cells. J Bone Miner Res. 1990;5:179–186
  45. Howell TH, Fiorellini JP, Paquette DW, Offenbacher S, Giannobile WV, Lynch SE. A phase I/II clinical trial to evaluate a combination of recombinant human platelet-derived growth factor-BB and recombinant human insulin-like growth factor-I in patients with periodontal disease. J Periodontol. 1997;68:1186–1193
  46. Yu H, Rohan T. Role of the insulin-like growth factor family in cancer development and progression. JNCI. 2000;92:1472–1489
  47. Firth SM, Baxter RC. Cellular actions of the Insulin-like growth factor binding proteins. Endocr Rev. 2002;23:824–854
  48. He Y, Macarak EJ, Korostoff JM, Howard PS. Compression and tension: differential effects on matrix accumulation by periodontal ligament fibroblasts in vitro. Connect Tissue Res. 2004;45:28–39
  49. Meikle MC. The tissue, cellular, and molecular regulation of orthodontic tooth movement: 100 years after Carl Sandstedt. Eur J Orthod. 2006;28:221–240
  50. Iqbal J, Zaidi M. Molecular regulation of mechanotransduction. Biochem Biophys Res Commun. 2005;328:751–755
  51. Eliceiri BP. Integrin and growth factor receptor crosstalk. Circ Res. 2001;89:1104–1110
  52. Yamaguchi M, Ogata N, Shinoda Y, Akune T, Kamekura S, Terauchi Y, et al. Insulin receptor substrate-1 is required for bone anabolic function of parathyroid hormone in mice. Endocrinology. 2005;146:2620–2628
  53. King GJ, Keeling SD, McCoy EA, Ward TH. Measuring dental drift and orthodontic tooth movement in response to various initial forces in adult rats. Am J Orthod Dentofacial Orthop. 1991;99:456–465
  54. Gonzales C, Hotokezaka H, Yoshimatsu M, Yozgatian JH, Darendeliler MA, Yoshida N. Force magnitude and duration effects on amount of tooth movement and root resorption in the rat molar. Angle Orthod. 2007;78:502–509

PII: S0003-9969(10)00004-X

doi: 10.1016/j.archoralbio.2010.01.002

Archives of Oral Biology
Volume 55, Issue 3 , Pages 215-222 , March 2010

Article Tools

* Image Usage & Resolution